BDBM92508 DP 00477, 3

SMILES FC(F)(F)c1cccc(NC(=O)C(C#N)C(=S)Nc2ccccc2Cl)c1

InChI Key InChIKey=JBTPUMQIJZGWRT-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92508   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM92508(DP 00477, 3)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM92508(DP 00477, 3)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 0.01% Triton-X by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM92508(DP 00477, 3)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 5 mM GSH by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM92508(DP 00477, 3)
Affinity DataKi:  1.84E+3nM IC50: 3.31E+4nMpH: 6.5Assay Description:The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed