BDBM91957 Chk1_89

SMILES c1cc(cc2c1cc(cc2)NC(=O)Nc3cnc(cn3)C#N)C(=O)O

InChI Key InChIKey=CACMTVGXYAZZNY-UHFFFAOYSA-N

Data  3 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 91957   

LigandPNGBDBM91957(Chk1_89)
Affinity DataIC50: 40nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM91957(Chk1_89)
Affinity DataKi:  40.4nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R
PDB3D3D Structure (crystal)
LigandPNGBDBM91957(Chk1_89)
Affinity DataKi:  126nMAssay Description:ChemBL affinity - Published Abbott papersMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM91957(Chk1_89)
Affinity DataKi:  126nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)