BDBM86133 LDHA Inhibitor, 29

SMILES Cc1nc2ccc(cc2s1)NC(=O)CCNC(=O)NCCc3ccc(cc3)CC(C(=O)O)C(=O)O

InChI Key InChIKey=GADNEHRFYQNKCC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86133   

TargetL-lactate dehydrogenase A chain(Rat)
Astrazeneca

LigandPNGBDBM86133(LDHA Inhibitor, 29)
Affinity DataKd:  69nMpH: 7.4Assay Description:A BIAcore 3000 or a BIAcore S51 instrument (GE Healthcare) was used to detect binding interactions using a direct binding assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Rat)
Astrazeneca

LigandPNGBDBM86133(LDHA Inhibitor, 29)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay using lactate dehydrogenase A (LDHA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)