BDBM82031 2-Oxoado (isoguanosine)::CAS_1818-71-9::isoguanosine

SMILES C1=NC2=C(NC(=O)N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

InChI Key InChIKey=MIKUYHXYGGJMLM-UHFFFAOYSA-N

Data  4 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 82031   

TargetAdenosine receptor A1(Guinea pig)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM82031(CAS_1818-71-9 | isoguanosine | 2-Oxoado (isoguanos...)
Affinity DataEC50:  1.15E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82031(CAS_1818-71-9 | isoguanosine | 2-Oxoado (isoguanos...)
Affinity DataKi:  94nMAssay Description:Affinity for Adenosine A1 receptor determined by [3H]N6-cyclohexyladenosine binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82031(CAS_1818-71-9 | isoguanosine | 2-Oxoado (isoguanos...)
Affinity DataKi:  94.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82031(CAS_1818-71-9 | isoguanosine | 2-Oxoado (isoguanos...)
Affinity DataKi:  331nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82031(CAS_1818-71-9 | isoguanosine | 2-Oxoado (isoguanos...)
Affinity DataKi:  331nMAssay Description:Affinity for Adenosine A2 receptor determined by [3H]NECA binding to rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article