BDBM81972 (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE::Alpha-Methylhistamine-S::CAS_75614-93-6

SMILES C[C@H](N)Cc1cnc[nH]1

InChI Key InChIKey=XNQIOISZPFVUFG-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 81972   

TargetPlatelet-activating factor receptor(Guinea pig)
Paris Diderot University

Curated by ChEMBL
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PAF-induced rabbit platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  9nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetHrh3 protein(Rat)
UnitÉ

Curated by PDSP Ki Database
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  14.3nMAssay Description:In vitro inhibition of [3H]-C18 PAF binding to human platelet membrane Platelet activating factor receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetHrh3 protein(Rat)
UnitÉ

Curated by PDSP Ki Database
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetHistamine H3 receptor(Guinea pig)
UnitÉ

Curated by PDSP Ki Database
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetHrh3 protein(Rat)
UnitÉ

Curated by PDSP Ki Database
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetHrh3 protein(Rat)
UnitÉ

Curated by PDSP Ki Database
LigandPNGBDBM81972(CAS_75614-93-6 | (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE...)
Affinity DataKi:  470nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed