BDBM81438 CDK Inhibitor, 11

SMILES CC1=C(SC(=O)N1C)c2ccnc(n2)Nc3ccc(cc3)S(=O)(=O)NCCOC

InChI Key InChIKey=WQZVTNFUNLTGDW-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 81438   

TargetCyclin-dependent kinase 2(Human)
Cyclacel

LigandPNGBDBM81438(CDK Inhibitor, 11)
Affinity DataKi:  0.110nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 1(Human)
Cyclacel

LigandPNGBDBM81438(CDK Inhibitor, 11)
Affinity DataKi:  4.10nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Cyclacel

LigandPNGBDBM81438(CDK Inhibitor, 11)
Affinity DataKi:  14nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Cyclacel

LigandPNGBDBM81438(CDK Inhibitor, 11)
Affinity DataKi: >500nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Cyclacel

LigandPNGBDBM81438(CDK Inhibitor, 11)
Affinity DataKi:  940nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed