BDBM7973 2-aminoethan-1-ol::CHEMBL104943::ethanolamine

SMILES C(CO)N

InChI Key InChIKey=HZAXFHJVJLSVMW-UHFFFAOYSA-N

Data  3 KI

PDB links: 62 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7973   

LigandPNGBDBM7973(CHEMBL104943 | 2-aminoethan-1-ol | ethanolamine)
Affinity DataKi:  1.93E+7nM ΔG°:  -2.38kcal/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rat)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM7973(CHEMBL104943 | 2-aminoethan-1-ol | ethanolamine)
Affinity DataKi:  9.03E+5nMAssay Description:Inhibition of [3H]choline brain uptake through choline transporter was determined in situ brain perfusion studies in Male Fischer-344 ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetHigh affinity choline transporter 1(Mouse)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM7973(CHEMBL104943 | 2-aminoethan-1-ol | ethanolamine)
Affinity DataKi:  1.50E+8nMAssay Description:Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed