BDBM770276 N-(2-(((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[1,5-a]pyridine-8-carbonyl)piperidin-3-yl)amino)-2-oxoethyl)-2,2,2-trifluoroacetamide::WO2024107778, Compound 62

SMILES O=C(CNC(=O)C(F)(F)F)N[C@@H]1CN(C(=O)c2cccn3cncc23)CC[C@H]1c1cc(F)cc(Cl)c1

InChI Key InChIKey=JTFUZYAAZRFGIW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770276   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770276BDBM770276(N-(2-(((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataIC50: 30.3nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetAngiotensin-converting enzyme 2(Human)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770276BDBM770276(N-(2-(((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataEC50:  2.00E+3nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778