BDBM73209 (+)-CIS-DIOXOLANE::CHEMBL105457::MLS000069362::SMR000058762::cid_657346::methamilane methiodide::trimethyl-[[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]methyl]ammonium;iodide::trimethyl-[[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]methyl]azanium;iodide

SMILES C[C@H]1OC[C@@H](C[N+](C)(C)C)O1

InChI Key InChIKey=COSSAOQSSXDIQW-UHFFFAOYSA-N

Data  11 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 73209   

TargetG protein-activated inward rectifier potassium channel 1(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataEC50:  0.280nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetMuscarinic acetylcholine receptor M1(Human)
University of Arizona

Curated by PDSP Ki Database
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2011
Entry Details
PubMed
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  6.40nMAssay Description:In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetMuscarinic acetylcholine receptor M2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to human cloned muscarinic M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  2.10E+3nMAssay Description:In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetMuscarinic acetylcholine receptor M4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  8.91E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M4 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Arizona

Curated by PDSP Ki Database
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Arizona

Curated by PDSP Ki Database
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to human cloned muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  1.35E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  2.19E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM73209(cid_657346 | methamilane methiodide | trimethyl-[[...)
Affinity DataKi:  2.19E+4nMAssay Description:Binding affinity to human cloned muscarinic M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed