BDBM68263 Microlactone, 15h

SMILES c1c(c2c(c(c1O)Cl)CC(=O)CCCCC\C=C\CCOC2=O)O

InChI Key InChIKey=VZTAZMSAAIUZJV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68263   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68263(Microlactone, 15h)
Affinity DataIC50: 760nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68263(Microlactone, 15h)
Affinity DataIC50: 160nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68263(Microlactone, 15h)
Affinity DataIC50: 100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)