BDBM67029 (1S,3R,6E,8R,10S,13R,14S,15R,17S,20E,24E,26S)-3,7,8,15,17,20-hexamethyl-5-methylidene-8,10,13,14-tetrakis(oxidanyl)-18,27-dioxabicyclo[24.1.0]heptacosa-6,20,24-triene-12,19-dione::(1S,3R,6E,8R,10S,13R,14S,15R,17S,20E,24E,26S)-8,10,13,14-tetrahydroxy-3,7,8,15,17,20-hexamethyl-5-methylene-18,27-dioxabicyclo[24.1.0]heptacosa-6,20,24-triene-12,19-dione::(1S,3R,6E,8R,10S,13R,14S,15R,17S,20E,24E,26S)-8,10,13,14-tetrahydroxy-3,7,8,15,17,20-hexamethyl-5-methylene-18,27-dioxabicyclo[24.1.0]heptacosa-6,20,24-triene-12,19-quinone::(1S,3R,6E,8R,10S,13R,14S,15R,17S,20E,24E,26S)-8,10,13,14-tetrahydroxy-3,7,8,15,17,20-hexamethyl-5-methylidene-18,27-dioxabicyclo[24.1.0]heptacosa-6,20,24-triene-12,19-dione::MLS002320521::SMR001338806::amphidinolide B1::cid_21773232

SMILES C[C@H]1C[C@@H]2O[C@H]2\C=C\CC\C=C(C)\C(=O)O[C@@H](C)C[C@@H](C)[C@H](O)[C@@H](O)C(=O)C[C@@H](O)C[C@@](C)(O)\C(C)=C\C(=C)C1

InChI Key InChIKey=PYXZGBVSQBXPDQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67029   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM67029(MLS002320521 | (1S,3R,6E,8R,10S,13R,14S,15R,17S,20...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay