BDBM667864 US20240122941, Compound 1::US20240122941, Compound 2::US20240122941, Compound 3::US20240122941, Compound 4

SMILES CNC(=O)Cn1cc(cn1)-c1ccc2c(c1)C(F)CC21NC(=O)N(CC(=O)N(Cc2ccc(F)cc2)C(C)C(F)(F)F)C1=O

InChI Key InChIKey=SWXCHCQCWFXILM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 667864   

TargetHistone acetyltransferase p300(Human)
National Cancer Center

US Patent
LigandPNGBDBM667864(US20240122941, Compound 1 | US20240122941, Compoun...)
Affinity DataIC50: 890nMAssay Description:SensoLyte HAT (p300) Assay Kit (ANASPEC, AS-72172) was used to assess the HAT activity inhibiting capability of a HAT inhibitor. Specifically, 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase p300(Human)
National Cancer Center

US Patent
LigandPNGBDBM667864(US20240122941, Compound 1 | US20240122941, Compoun...)
Affinity DataIC50: 1.31E+4nMAssay Description:SensoLyte HAT (p300) Assay Kit (ANASPEC, AS-72172) was used to assess the HAT activity inhibiting capability of a HAT inhibitor. Specifically, 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase p300(Human)
National Cancer Center

US Patent
LigandPNGBDBM667864(US20240122941, Compound 1 | US20240122941, Compoun...)
Affinity DataIC50: 1.16E+3nMAssay Description:SensoLyte HAT (p300) Assay Kit (ANASPEC, AS-72172) was used to assess the HAT activity inhibiting capability of a HAT inhibitor. Specifically, 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase p300(Human)
National Cancer Center

US Patent
LigandPNGBDBM667864(US20240122941, Compound 1 | US20240122941, Compoun...)
Affinity DataIC50: 6.10nMAssay Description:SensoLyte HAT (p300) Assay Kit (ANASPEC, AS-72172) was used to assess the HAT activity inhibiting capability of a HAT inhibitor. Specifically, 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent