BDBM6670 4-({6-[(2,6-dichlorophenyl)carbonyl]imidazo[1,2-a]pyridin-2-yl}amino)benzene-1-sulfonamide::aminoimidazo[1,2-a]pyridine deriv. 2i

SMILES c1cc(c(c(c1)Cl)C(=O)c2ccc3nc(cn3c2)Nc4ccc(cc4)S(=O)(=O)N)Cl

InChI Key InChIKey=UQAWGIKJINAKIZ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6670   

LigandPNGBDBM6670(4-({6-[(2,6-dichlorophenyl)carbonyl]imidazo[1,2-a]...)
Affinity DataIC50: 560nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2005
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM6670(4-({6-[(2,6-dichlorophenyl)carbonyl]imidazo[1,2-a]...)
Affinity DataIC50: 390nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2005
Entry Details Article
PubMed
LigandPNGBDBM6670(4-({6-[(2,6-dichlorophenyl)carbonyl]imidazo[1,2-a]...)
Affinity DataIC50: 1.34E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2005
Entry Details Article
PubMed