BDBM665895 US20240116922, Comparator 2B

SMILES Cc1cnc2c(cnn2c1)NC(=O)c3cn4cc(nc4nc3OC(C)C)C56CC(C5)(OC6)C

InChI Key InChIKey=DEQCXGYERMCXNL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665895   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent

LigandBDBM665895(US20240116922, Comparator 2B)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/29/2024
Entry Details
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PDB3D Structure (crystal)
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