BDBM665716 US20240116922, Example 18

SMILES CC(C)Oc1c(cn2cc(nc2n1)C34CC(C3)(OC4)C)C(=O)NC5=CC=CN(C5=O)C6CC6

InChI Key InChIKey=JJZLDWBCAMPSMG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665716   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent

LigandBDBM665716(US20240116922, Example 18)Copy SMILESCopy InChI

Affinity DataIC50: 0.200nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/29/2024
Entry Details
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PDB3D Structure (crystal)
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