BDBM649469 US11890288, Compound 1

SMILES COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(cc1)-c1ccc(cc1)C(=O)NCc1ccc(cc1)S(=O)(=O)Nc1ccc(C)c2c(c[nH]c12)C#N

InChI Key InChIKey=HHSZFSOLNUHGMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649469   

TargetBromodomain-containing protein 4(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM649469(US11890288, Compound 1)
Affinity DataIC50: 29nMAssay Description:The inhibitory action of the compound of the present invention on the binding of BRD4 protein and a ligand thereof (acetylated histone H4) was evalua...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
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