BDBM595074 US11584714, Compound 1102

SMILES [H]/N=C(/c1ccc(cc1)CNC(=O)[C@@H]2CCN2C(=O)[C@@H](C3CCCCC3)NCC(=O)N)\N

InChI Key InChIKey=HGGAEWPXSYIPSZ-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595074   

TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM595074(US11584714, Compound 1102)
Affinity DataKi: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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PDB3D3D Structure (crystal)
TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595074(US11584714, Compound 1102)
Affinity DataKi:  1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent