BDBM588541 2-amino-9-[(5R,7R,8R,12aR,14R,15aS,16R)-2,10,16-trihydroxy-2,10-dioxido-14- (pyrimidin-4-yloxy)decahydro-5,8-methanocyclopenta[1][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9-dihydro-6H-purin-6-one::US11542293, Compound I-10

SMILES c1cncnc1O[C@@H]2C[C@@H]3COP(=O)(O[C@@H]4[C@@H]([C@@H](COP(=O)(O[C@H]3C2)O)O[C@H]4n5cnc6c5N=C(NC6=O)N)O)O

InChI Key InChIKey=IQDCEFNXFAZHCY-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588541   

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM588541(2-amino-9-[(5R,7R,8R,12aR,14R,15aS,16R)-2,10,16-tr...)
Affinity DataIC50: 1.00E+3nMAssay Description:40 nL of test compounds in DMSO were added to wells in a white, 384 well microtitre plate (Greiner 784075). 2 uL STING assay buffer (PBS and 0.01% BS...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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PDB3D3D Structure (crystal)