BDBM568489 (R)-(3-Aminopiperidin-1-yl)(2-(1-(4-fluorobenzyl)-1H-indol-2-yl)-3-methylimidazo[1,2-a]pyridin-7-yl)methanone::US11426412, Compound 13

SMILES Cc1c(nc2cc(ccn12)C(=O)N1CCC[C@@H](N)C1)-c1cc2ccccc2n1Cc1ccc(F)cc1

InChI Key InChIKey=DUVCPNSLXBKGOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568489   

TargetProtein-arginine deiminase type-4(Human)
Jubilant Epipad

US Patent
LigandPNGBDBM568489((R)-(3-Aminopiperidin-1-yl)(2-(1-(4-fluorobenzyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Citrullination assay was detected via ammonia release. PAD4 was diluted to 120 nM in assay buffer (100 mM HEPES, 50 mM NaCl, 2 mM DDT, 0.6 mg/mL BSA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetProtein-arginine deiminase type-4(Human)
Jubilant Epipad

US Patent
LigandPNGBDBM568489((R)-(3-Aminopiperidin-1-yl)(2-(1-(4-fluorobenzyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds with PAD4 was detected by FP assay. PAD4 was diluted to 1 uM in assay buffer (100 mM HEPES, 50 mM NaCl, 1 mM DTT, 5% Glycerol an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent