BDBM560668 US11384066, Example LY3295668

SMILES Cc1cc(n[nH]1)Nc2ccc(c(n2)C[C@]3(CCN([C@@H](C3)C)Cc4cccc(c4F)Cl)C(=O)O)F

InChI Key InChIKey=YQQZZYYQTCPEAS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560668   

TargetAurora kinase A(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560668(US11384066, Example LY3295668)
Affinity DataIC50: 1nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetAurora kinase B(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560668(US11384066, Example LY3295668)
Affinity DataIC50: 740nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent