BDBM549691 US11306078, Example 1.107::rac-5-(2,4,6-Trifluoro-phenyl)-isoxazole-3-carboxylic acid [(3R*,4R*)-3- (azetidine-1-carbonyl)-1-cyclopropylmethyl-piperidin-4-yl]-amide

SMILES Fc1cc(F)c(-c2cc(no2)C(=O)N[C@@H]2CCN(CC3CC3)C[C@H]2C(=O)N2CCC2)c(F)c1

InChI Key InChIKey=PEWKTPNTEBJBLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549691   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 549691BDBM549691(rac-5-(2,4,6-Trifluoro-phenyl)-isoxazole-3-carboxy...)
Affinity DataIC50: 520nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2022
Entry Details
US Patent