BDBM544457 (2S)-3-Phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic acid; hydrochloride::US11286249, Example 17

SMILES c1ccc(cc1)C[C@@H]([C@H]2CCNC2)C(=O)O

InChI Key InChIKey=OSTNIMGVYREMID-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 544457   

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544457((2S)-3-Phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic ac...)
Affinity DataIC50: 152nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
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PDB3D3D Structure (crystal)