BDBM520651 US11147816, PD318088::US11701360, PD318088

SMILES c1cc(c(cc1I)F)Nc2c(cc(c(c2F)F)Br)C(=O)NOC[C@H](CO)O

InChI Key InChIKey=XXSSGBYXSKOLAM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520651   

LigandPNGBDBM520651(US11147816, PD318088 | US11701360, PD318088)
Affinity DataIC50: 1.40nMAssay Description:The IC50 for MEK1 and 2 can be measured by methods in references such as [Yamaguchi et al. (2011) International Journal of Oncology 39:23-31].More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM520651(US11147816, PD318088 | US11701360, PD318088)
Affinity DataIC50: 1.40nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)