BDBM513956 US11059824, Compound loxoribine

SMILES C=CCN1C2=C(N=C(NC2=O)N)N(C1=O)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

InChI Key InChIKey=VDCRFBBZFHHYGT-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513956   

TargetToll-like receptor 7(Human)
Primmune Therapeutics

US Patent
LigandPNGBDBM513956(US11059824, Compound loxoribine)
Affinity DataEC50:  3.22E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)