BDBM50615658 CHEMBL5276516

SMILES c1cc(c(c(c1)Cl)C(=O)n2c3cccnc3c(n2)c4cc(c(cc4F)C(=O)O)O)C(F)(F)F

InChI Key InChIKey=VYMOEMKHCRZWMT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50615658   

TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615658(CHEMBL5276516)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in Escherichia coli BL21(DE3) cell measured after 16 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)