BDBM50614316 CHEMBL3546188

SMILES B1(c2cc(ccc2CO1)Oc3ccc(cc3F)CN)O

InChI Key InChIKey=TUWUQFIFQVYZSK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614316   

TargetRho-associated protein kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50614316(CHEMBL3546188)
Affinity DataIC50: 810nMAssay Description:Inhibition of GST-tagged ROCK1 (1 to 535 residues) (unknown origin) using S6-peptide as substrate preincubated for 15 mins followed by 33P-ATP additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50614316(CHEMBL3546188)
Affinity DataIC50: 540nMAssay Description:Inhibition of GST-tagged ROCK2 (5 to 554 residues) (unknown origin) using S6-peptide as substrate preincubated for 15 mins followed by 33P-ATP additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)