BDBM50613892 CHEMBL5280882

SMILES c1cc(cc(c1)F)[C@H]2CN(C[C@@H]2CN3CCC(CC3)CCS(=O)(=O)c4ccc(cc4)F)CC5(CCCC5)C(=O)O

InChI Key InChIKey=JLKKIAYYHXNZIY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613892   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613892(CHEMBL5280882)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613892(CHEMBL5280882)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)