BDBM50613881 CHEMBL5271123

SMILES CCc1c(nn(c1C2CCN(CC2)C[C@H]3CN(C[C@@H]3c4cccc(c4)F)CC5(CCCC5)C(=O)O)CC)CC

InChI Key InChIKey=PCCHYTAFAXFIAW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613881   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613881(CHEMBL5271123)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613881(CHEMBL5271123)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)