BDBM50613701 CHEBI:17825::CHEMBL1232939

SMILES C[n+]1cn(c2c1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O

InChI Key InChIKey=AOKQNZVJJXPUQA-UHFFFAOYSA-O

Data  1 IC50  1 Kd

PDB links: 382 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613701   

TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613701(CHEMBL1232939 | CHEBI:17825)
Affinity DataKd:  3.90E+3nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613701(CHEMBL1232939 | CHEBI:17825)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed