BDBM50612390 CHEMBL5278485

SMILES CC(C)(C)c1cc(ccc1O)N(Cc2ccccc2)C(=O)c3c(cc(cc3Cl)N(C)C)Cl

InChI Key InChIKey=IDACWMHIKWNAEO-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50612390   

TargetBile acid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50612390(CHEMBL5278485)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at FXR in human HepG2 cells incubated for 24 hrs by dual luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)