BDBM50611355 CLN-081::CLN081::Cln 081::Cln-081::TAS-6417::TAS6417::TPC-064::TPC064::Zipalertinib

SMILES CC1=C[C@@H](Cn2c1c(-c1cnc3ccccc3c1)c1c(N)ncnc21)NC(=O)C=C

InChI Key InChIKey=MKCYPWYURWOKST-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611355   

TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50611355(Zipalertinib | Cln 081 | Cln-081 | CLN-081 | CLN08...)
Affinity DataIC50: 8nMAssay Description:Inhibition of wildtype EGFR (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50611355(Zipalertinib | Cln 081 | Cln-081 | CLN-081 | CLN08...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of EGFR-D770-N771insNPG mutant (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50611355(Zipalertinib | Cln 081 | Cln-081 | CLN-081 | CLN08...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed