BDBM50609300 CHEMBL5266562

SMILES CNCCNCc1cccc(c1)-c1nc(Nc2ccccc2)c(C)c(n1)-c1c(C)noc1C

InChI Key InChIKey=DVIUIRPCVXVFSX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50609300   

TargetProtein arginine N-methyltransferase 3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PRMT1 (unknown origin) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human CARM1 (140 to 480 residues) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 490nMAssay Description:Inhibition of PRMT6 (unknown origin) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 920nMAssay Description:Inhibition of PRMT8 (unknown origin) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) incubated for 15 mins measured after 60 min by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PRMT7 (unknown origin) by radioisotope based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed