BDBM50608624 CHEMBL5274743

SMILES CC(C)CN(C[C@H]([C@H](Cc1ccccc1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)c4ccc(cc4)C(=O)O

InChI Key InChIKey=YSTCRWMBLFPEMC-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608624   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50608624(CHEMBL5274743)
Affinity DataKi:  13nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50608624(CHEMBL5274743)
Affinity DataKi:  13nMAssay Description:Binding affinity to HIV1 recombinant wild type protease expressed in Escherichia coli BL21(DE3) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50608624(CHEMBL5274743)
Affinity DataKi:  13nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)