BDBM50607294 CHEMBL5220178

SMILES Cc1ccccc1Oc2cc(c(cc2C#N)OC)N3C(=O)C=C(NC3=O)C(F)(F)F

InChI Key InChIKey=GSEHYSQYWAECFH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607294   

LigandPNGBDBM50607294(CHEMBL5220178)
Affinity DataIC50: 162nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50607294(CHEMBL5220178)
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed