BDBM50601992 CHEMBL5200645

SMILES CCCC1=C(/C(=C/C(=C\C=C\C(=C\C(=O)O)\C)/C)/CCC1)CCC(C)C

InChI Key InChIKey=AFPIKPIXJYHWHZ-UHFFFAOYSA-N

Data  2 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601992   

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50601992(CHEMBL5200645)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50601992(CHEMBL5200645)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50601992(CHEMBL5200645)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)