BDBM50601521 CHEMBL5092273

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(cc1)C(=O)NCCCCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C

InChI Key InChIKey=OFNZESNEBSQKSE-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601521   

TargetWD repeat-containing protein 5(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50601521(CHEMBL5092273)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to recombinant WDR5 (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by isothermal titration ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50601521(CHEMBL5092273)
Affinity DataIC50: 1.36E+4nMAssay Description:Displacement of N-(4'-((17-(5,5-difluoro-7-(1H-pyrrol-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-15-oxo-4,7,10-trioxa-14-azah...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50601521(CHEMBL5092273)
Affinity DataIC50: 2.15E+3nMAssay Description:Displacement of N-(4'-((17-(5,5-difluoro-7-(1H-pyrrol-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-15-oxo-4,7,10-trioxa-14-azah...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed