BDBM50601385 CHEMBL5192478

SMILES C1CC1C2=CC(=O)NC(=O)N2

InChI Key InChIKey=ABHXYFPEQCXJJJ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50601385   

TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601385(CHEMBL5192478)
Affinity DataIC50: 1.74E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601385(CHEMBL5192478)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to GST-tagged YTHDC1 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing family protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601385(CHEMBL5192478)
Affinity DataIC50: 3.79E+5nMAssay Description:Binding affinity to GST-tagged YTHDF1 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 3(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601385(CHEMBL5192478)
Affinity DataIC50: 2.18E+5nMAssay Description:Binding affinity to GST-tagged YTHDF3 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601385(CHEMBL5192478)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)