BDBM50601384 CHEMBL5205586

SMILES CNc1ncnc2c([nH]nc12)-c1ccccc1

InChI Key InChIKey=XIEMFNUUOUPBSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601384   

TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601384(CHEMBL5205586)
Affinity DataIC50: 1.61E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601384(CHEMBL5205586)
Affinity DataIC50: 1.42E+5nMAssay Description:Binding affinity to GST-tagged YTHDC1 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601384(CHEMBL5205586)
Affinity DataIC50: 4.91E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed