BDBM50600028 CHEMBL5190816

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cc3)-c3csc4c3oc(cc4=O)N3CCOCC3)nc2n1C1CCCC1

InChI Key InChIKey=XJKTXWSMMWPNTP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50600028   

TargetCyclin-dependent kinase 9(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal His-tagged human recombinant BRD4 BD1 (44 to 460 residues) expressed in Escherichia coli using acetylated-histone peptide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 89nMAssay Description:Inhibition of N-terminal His-tagged human recombinant BRD4 BD2 (44 to 460 residues) expressed in Escherichia coli using acetylated-histone peptide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50600028(CHEMBL5190816)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed