BDBM50599333 CHEMBL5180830

SMILES c1ccc(cc1)CN2c3ccccc3Nc4ccc(cc4C2=O)F

InChI Key InChIKey=KPJCQYLIQBFEHH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599333   

TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599333(CHEMBL5180830)
Affinity DataIC50: 52nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599333(CHEMBL5180830)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)