BDBM50597474 CHEMBL5171140

SMILES C[C@H](c1cccc(c1)OC)NC(=O)N2CCC(CC2)c3ccncc3

InChI Key InChIKey=TUPUYLLHTGZRRB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597474   

TargetRho-associated protein kinase 2(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597474(CHEMBL5171140)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 1(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597474(CHEMBL5171140)
Affinity DataIC50: 5.28E+4nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human PKG expressed in baculovirus infected Sf9 insect cells using RSK as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed