BDBM50591265 CHEMBL5188870

SMILES CCN(c1cccc(c1)C)C(=O)COc2c(c(c(c(n2)C)Br)C(F)(F)F)C#N

InChI Key InChIKey=OFTSRQPYUSQTEG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591265   

TargetDNA polymerase theta(Human)
Artios Pharma

Curated by ChEMBL
LigandPNGBDBM50591265(CHEMBL5188870)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human full length DNA polymerase theta using DNA substrate measured after 1 hrs in presence of dNTPs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)