BDBM50587656 CHEMBL5193416

SMILES c1cc2c3cc1C(=O)NS(=O)(=O)CCOCCCCCCN3C[C@@]4(CCc5c4ccc(c5)Cl)CO2

InChI Key InChIKey=QBWGEQPNKKSGAL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587656   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50587656(CHEMBL5193416)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and TAMRA labeled Bim BH3 peptide interaction us...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/18/2023
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL