BDBM50587655 CHEMBL5183445

SMILES c1ccc(cc1)CS(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H](O3)c4ccc(cc4Cl)Cl)CC5CCC5

InChI Key InChIKey=HEKXNQLQQLOBSI-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587655   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50587655(CHEMBL5183445)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and TAMRA labeled Bim BH3 peptide interaction us...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/18/2023
Entry Details
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