BDBM50587565 CHEMBL5081226

SMILES CC(C)(c1ncccn1)NC2=CC(=O)N(c3c2cc(cc3)Nc4ccnc(c4C#N)Cl)C

InChI Key InChIKey=HVBNNNFJPKGPQA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587565   

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50587565(CHEMBL5081226)
Affinity DataIC50: 46nMAssay Description:Inhibition of human BCL6 (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 peptide as substrate measured after 2 hrs by TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50587565(CHEMBL5081226)
Affinity DataIC50: 470nMAssay Description:Inhibition of human nanoLuc-tagged BCL6 expressed in HEK293T cells coexpressing HaloTag-SMRT using NanoBRET furimazine substrate incubated for 6 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)