BDBM50587482 CHEMBL5073515

SMILES Cc1c(cc2c3cccc(c3[nH]c2n1)C4CC4)C(=O)OC

InChI Key InChIKey=PMYXVYACIJANSL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587482   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587482(CHEMBL5073515)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587482(CHEMBL5073515)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed