BDBM50586779 CHEMBL5073596

SMILES C[C@@H]1CN(CCN1CC(F)(F)F)C(=O)c2cc(ccc2F)CN3c4ccccc4C(=O)NC3=O

InChI Key InChIKey=WJSBPAZKQYZPAE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586779   

TargetPoly [ADP-ribose] polymerase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50586779(CHEMBL5073596)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human PARP1 using NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50586779(CHEMBL5073596)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human PARP2 using NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed