BDBM50586500 CHEMBL5078591::US20240139189, Compound 21

SMILES CC1(CCN(CC1)Cc2ccc(cc2F)N3CC(=O)NC4(C3)CCN(CC4)c5cc(ncn5)NC)C

InChI Key InChIKey=IYZMNTMLBDUPPA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586500   

TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50586500(CHEMBL5078591 | US20240139189, Compound 21)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase non-catalytic subunit(Human)
University of Zurich

US Patent
LigandPNGBDBM50586500(CHEMBL5078591 | US20240139189, Compound 21)
Affinity DataIC50: 32nMAssay Description:No details are given in this patent.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)