BDBM50584824 CHEMBL5080665

SMILES CNC(=O)CCC(=O)N1CCC[C@H]1C(=O)N[C@@H]2COC(=O)c3ccccc3CSC[C@@H](NC2=O)C(=O)N(C)C

InChI Key InChIKey=DXVZHGSXTJTODF-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584824   

TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50584824(CHEMBL5080665)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50584824(CHEMBL5080665)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)