BDBM50583521 CHEMBL5077230

SMILES CCC(=O)Nc1cc(ccc1Nc1ncc2CCc3c(ccn3-c2n1)C(=O)Nc1c(CC)cccc1CC)N1CCN(C)CC1

InChI Key InChIKey=OFKCTLDDZSLLFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50583521   

TargetDual specificity protein kinase TTK(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50583521(CHEMBL5077230)
Affinity DataIC50: 33nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50583521(CHEMBL5077230)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed